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Ibuprofen is administered as a racemic mixture. The R-enantiomer undergoes extensive interconversion to the S-enantiomer in vivo . The S-enantiomer is believed to be the more pharmacologically active enantiomer.  The R-enantiomer is converted through a series of three main enzymes. These enzymes include acyl-CoA-synthetase, which converts the R-enantiomer to (-)-R-ibuprofen I-CoA; 2-arylpropionyl-CoA epimerase, which converts (-)-R-ibuprofen I-CoA to (+)-S-Ibuprofen I-CoA; and hydrolase, which converts (+)-S-ibuprofen I-CoA to the S-enantiomer.  In addition to the conversion of ibuprofen to the S-enantiomer, the body can metabolize ibuprofen to several other compounds, including numerous hydroxyl, carboxyl and glucuronyl metabolites. Virtually all of these have no pharmacological effects. 
Derived from cannabis plants like hemp, cannabinoids such as CBD interact with your native endocannabinoid system. This central system’s responsibility is to maintain the body’s homeostasis for a wide array of systems, including sleep, mood, anxiety, pain, appetite, and immune response. Each day, our outside environment influences your systems, causing them to fluctuate. The endocannabinoid system is constantly working to keeping them in balance. CBD and other cannabinoids support the efforts of this naturally occurring endocannabinoid system .