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In most naturally occurring unsaturated fatty acids, the hydrogen atoms are on the same side of the double bonds of the carbon chain ( cis configuration — from the Latin, meaning "on the same side"). However, partial hydrogenation reconfigures most of the double bonds that do not become chemically saturated, twisting them so that the hydrogen atoms end up on different sides of the chain. This type of configuration is called trans , from the Latin, meaning "across".  The trans configuration is the lower energy form, and is favored when catalytically equilibrated as a side reaction in hydrogenation.
The main symptoms of vitamin D overdose which are those of hypercalcemia including anorexia , nausea, and vomiting. These may be followed by polyuria , polydipsia , weakness, insomnia, nervousness, pruritus and ultimately renal failure . Furthermore, proteinuria , urinary casts , azotemia , and metastatic calcification (especially in the kidneys) may develop.  Other symptoms of vitamin D toxicity include mental retardation in young children, abnormal bone growth and formation, diarrhea, irritability, weight loss, and severe depression.