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Alan: In the research I’ve collaborated on thus far, I unfortunately can’t report anything spectacular. In fact, it’s some of the most anticlimactic/unsexy results in the literature (LOL). However, in the most recent RCT of ours that’s in publication (PMID: 28070459), we did report individual data, and one of the subjects showed approximately an 18 mm gain in biceps thickness ( inches), measured via ultrasound, over an 10-week period. The rest of the subjects – all of whom were resistance-trained – stayed pretty much the same, which was not surprising since they were in hypocaloric conditions. It’s interesting to imagine what type of response this high responder would have if conditions were optimized for muscle growth, and/or supplementation was implemented. On the poor responder side, one of the subjects experienced a huge drop in quadriceps thickness (25 mm; about 1 inch) during this study. Interindividual response variability is just the nature of the beast, and a very poignant example of this is work by Ahtiainen et al (PMID: 26767377), who demonstrated vast heterogeneity in subjects’ responses to resistance training. Their study is openly accessible, have a look at this figure showing the full range of differences in strength & size gains (and losses): https:///pmc/articles/PMC5005877/figure/Fig4/. High responders gained 4-5 times the muscle mass of average responders. Of course there are the unfortunate subjects (2% of the subjects were classified as low responders) who included those who experienced losses in size and strength as a result of resistance training (and in my speculation, other factors as well).