Nonsteroidal anti-inflammatory medications for pain and swelling

NSAIDs may reduce the benefit of drugs used for treating hypertension because NSAIDs may increase blood pressure . NSAIDs decrease the elimination of lithium ( Eskalith ) and methotrexate ( Rheumatrex ) potentially leading to their toxicity , and reduce the action of diuretics (" water pills") by reducing blood flow to the kidneys. NSAIDs increase bleeding by decreasing the activity of blood platelets and therefore formation of blood clots. When used with other drugs that also increase bleeding, for example, warfarin ( Coumadin ), the likelihood of bleeding complications is increased. Prolonged use of NSAIDs with drugs that increase bleeding should be avoided.

Sore throat usually is described as pain or discomfort in the throat area. A sore throat may be caused by bacterial infections, viral infections, toxins, irritants, trauma, or injury to the throat area. Common symptoms of a sore throat include a fever, cough, runny nose, hoarseness, earaches, sneezing, and body aches. Home remedies for a sore throat include warm soothing liquids and throat lozenges. OTC remedies for a sore throat include OTC pain relievers such as ibuprofen or acetaminophen. Antibiotics may be necessary for some cases of sore throat.

Coresatin Nonsteroidal Cream) is a topical skin cream, and as such, it must be applied as directed by the prescribing physician to the part of the skin that needs to be treated. Follow the directions provided by your physician. Generally speaking, adults treating psoriasis or other inflammatory skin conditions are instructed to apply it to the skin 3 to 6 times per day. Do not apply more of the cream than your physician tells you to. It is also important to note that the pediatric version of this cream should only be used to treat a child if a physician prescribes it for this purpose.

Meloxicam use can result in gastrointestinal toxicity and bleeding, headaches, rash, and very dark or black stool (a sign of intestinal bleeding). Like other NSAIDs , its use is associated with an increased risk of cardiovascular events such as heart attack and stroke . [5] It has fewer gastrointestinal side effects than diclofenac , [6] piroxicam , [7] naproxen , [8] and perhaps all other NSAIDs which are not COX-2 selective. [6] Although meloxicam inhibits formation of thromboxane A, it does not appear to do so at levels that would interfere with platelet function.

SOURCES: Byron Cryer, MD, spokesman, American Gastroenterological Association; associate professor of medicine, University of Texas Southwestern Medical Center, Dallas. Nieca Goldberg, MD, spokeswoman for the American Heart Association; chief of women's cardiac care, Lennox Hill Hospital, New York; author, Women Are Not Small Men: Lifesaving Strategies For Preventing And Healing Heart Disease In Women . John Klippel, MD, president and CEO, Arthritis Foundation, Atlanta. Scott Zashin, clinical assistant professor, University of Texas Southwestern Medical Center; author of Arthritis Without Pain . American College of Rheumatology web site. Arthritis Foundation web site. American Heart Association web site. American College of Gastroenterology web site. American Gastroenterological Association web site. American Academy of Family Physicians web site. American Academy of Allergy, Asthma, and Immunology web site.

Andrea Leigh Zaenglein, MD  Professor of Dermatology and Pediatrics, Department of Dermatology, Hershey Medical Center, Pennsylvania State University College of Medicine

Andrea Leigh Zaenglein, MD is a member of the following medical societies: American Academy of Dermatology , Society for Pediatric Dermatology

Disclosure: Received consulting fee from Galderma for consulting; Received consulting fee from Valeant for consulting; Received consulting fee from Promius for consulting; Received consulting fee from Anacor for consulting; Received grant/research funds from Stiefel for investigator; Received grant/research funds from Astellas for investigator; Received grant/research funds from Ranbaxy for other; Received consulting fee from Ranbaxy for consulting.

Nonsteroidal anti-inflammatory medications for pain and swelling

nonsteroidal anti-inflammatory medications for pain and swelling

Meloxicam use can result in gastrointestinal toxicity and bleeding, headaches, rash, and very dark or black stool (a sign of intestinal bleeding). Like other NSAIDs , its use is associated with an increased risk of cardiovascular events such as heart attack and stroke . [5] It has fewer gastrointestinal side effects than diclofenac , [6] piroxicam , [7] naproxen , [8] and perhaps all other NSAIDs which are not COX-2 selective. [6] Although meloxicam inhibits formation of thromboxane A, it does not appear to do so at levels that would interfere with platelet function.

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