The action of DEPO-MEDROL Sterile Aqueous Suspension injected intrasynovially appears to be well localized since significant metabolic effects characteristic of systemic administration of adrenal steroids have not been observed. In a few instances mild and transient improvement of structures other than those injected have been reported. No other systemic effects have been noted. However, it is possible that mild systemic effects may occur following intrasynovial administration, and this possibility is greater the larger the number of structures injected and the higher the total dose employed.
Strictly follow the instructions of a veterinarian when administering methylprednisolone. Each methylprednidolone tablet contains 4mg methylprednisolone. Dosage depends on several factors like severity of the condition, the mode of administration and the like. The same dosage pattern is followed for cats and dogs and this usually ranges from mg per pound (1 mg/kg) to 15 mg per pound (30 mg/kg). Divide the total dosage into equal parts and administer every 6 to 10 hours apart. The veterinarian might increase or cut down the duration of treatment as per the response to the medication and appearance of adverse effects. Avoid increasing the dosage, or stopping the treatment without consulting a veterinary expert.