30 mg/kg/dose (Max: 1 gram/dose) IV or IM once daily for 1 to 3 days. High-dose pulse steroids may be considered as an alternative to a second infusion of IVIG or for retreatment of patients who have had recurrent or recrudescent fever after additional IVIG, but should not be used as routine primary therapy with IVIG in patients with Kawasaki disease. Corticosteroid treatment has been shown to shorten the duration of fever in patients with IVIG-refractory Kawasaki disease or patients at high risk for IVIG-refractory disease. A reduction in the frequency and severity of coronary artery lesions has also been reported with pulse dose methylprednisolone treatment.
The treatment of psoriasis depends on the severity of the psoriasis. Think of the treatment of psoriasis as a flight of stairs. Each step represents a treatment of greater potency, but with more potential side effects. The treatment of psoriasis always starts at the bottom step, . the least potent treatment with the least potential side effects. If the treatment at this level does not work, the treatment can progress to the next level. This stepwise approach allows for control of the psoriasis with the least potent and safest medication possible.
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